This study aimed to analyze the glycemic index value of processed products of Coleus tuberosus. The study included ten healthy subjects with seven males, three females (30 ± 3.80 years on average age and 22.49 ± 1.82 on average BMI). Participants tested three different meals (D-glucose anhydrous, wheat crackers, and Coleus tuberosus crackers) with equal carbohydrate load (50 g). Blood glucose concentrations were measured at 0 min as well as at 15, 30, 45, 60, 90 and 120 min after the start of the meal for glucose levels determination. The result showed that the glycemic index of Coleus tuberosus crackers rich in resistant starch tipe 3 categorized in the low category. The glycemic index value of Coleus tuberosus crackers at 40.88 ± 6.42, whereas wheat crackers has high glycemic index (76.08 ± 5.36). Based on this results, Coleus tuberosus crackers is good for control of blood glucose profile. © All Rights Reserved.